The following are examples based on a systematic review of cost-effectiveness literature for selected prevention strategies. This review was conducted by the Centers for Disease Control and Prevention(CDC).
| Disease | Incidence | Medical Care Costs | Benefits of Early Detection | Costs of Early Detection / Screening |
| Breast cancer (Mammography) | 44,000 deaths / yr. 180,000 new cases / yr. | 6.5 billion | Reduces mortality by 30% | $60,000 per life year gained ($80 / mammogram) |
| Cervical cancer (PAP Smear) | 4,800 deaths / yr.; 14,500 new cases / yr. | Early stage: $4359 Late stage: $13,359/ case | Reduces mortality 20%-60% | $14,000 per life year gained |
Reference: Messonniew, M. L., et. al. 1999. An ounce of prevention - What are the returns? American Journal of Preventive Medicine 16(3).